The period anchored movement disorders in clear brain circuit terms, foregrounding brainstem reticular networks and pallidal pathways as central engines of tremor and eye movement abnormalities. Researchers began to unify cortical, basal ganglia, and brainstem circuits to explain voluntary movement, setting the stage for wiring-based theories of motor dysfunction. Methodologically, the period favored anatomical–physiological correlations and early surgical interventions that demonstrated the modulability of tremor through circuit disruption.